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Aciclovir Tablets for Cold Sores

Dr Roger Henderson
Reviewed by Roger HendersonReviewed on 29.04.2024 | 4 minutes read
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Aciclovir is an antiviral medication that helps manage and reduce the effects of cold sores caused by the Herpes Simplex virus (HSV). Cold sores are common, and once someone has contracted the virus, it remains dormant in the body, often resurfacing when triggered by stress, fatigue, sun exposure, or even a change in weather. While over-the-counter treatments like Zovirax cream contain aciclovir in topical form, the tablet version requires a doctor’s prescription due to its stronger potency and systemic effect.

Doctor’s advice

Who Can Benefit from Aciclovir Tablets?

Aciclovir tablets can be a key part of managing cold sores, especially for individuals who experience frequent outbreaks or have a weakened immune system. It works by reducing the severity of symptoms during an active outbreak and can also prevent future episodes if taken regularly. For people who suffer from cold sores multiple times a year, the tablets can serve as a preventive treatment to lessen the frequency and intensity of outbreaks.

The medication is also effective for treating outbreaks in other areas of the body caused by the Herpes Simplex virus, such as genital herpes or herpes zoster (shingles).

When treating a cold sore outbreak, it is important to begin aciclovir treatment as soon as you notice the early signs — typically a tingling or burning sensation. The medication is most effective if started within 5 days of the first symptoms appearing.

How does Aciclovir Tablets work?

Aciclovir is an antiviral agent that inhibits the replication of the Herpes Simplex virus at a cellular level. It works by interfering with the viral DNA synthesis, halting the virus from multiplying. This allows the body's immune system to combat the virus more effectively.

In the case of an active cold sore outbreak, aciclovir tablets are typically prescribed at a higher dose for a short duration — usually 5 days. This short, intense course of treatment helps reduce the duration of the outbreak and alleviate symptoms. For individuals who are immunocompromised, such as those undergoing chemotherapy or living with HIV, aciclovir is often prescribed in higher doses to manage the virus effectively.

For those with frequent outbreaks, aciclovir can also be prescribed as a suppressive treatment. This means taking lower doses of the medication on a daily basis to prevent future outbreaks or reduce their severity.

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How to Take Aciclovir Tablets

When you first notice the early signs of a cold sore outbreak — a tingling or itching sensation at the site — it is crucial to start taking aciclovir tablets immediately. The sooner you begin the treatment, the more effective it will be. The typical dosage for treating an active outbreak is a high dose over a 5-day period. For people with weakened immune systems, the dosage might be higher.

For preventive treatment, aciclovir is usually taken on a long-term basis, often daily, to reduce the frequency and intensity of outbreaks. It's essential to follow the doctor’s instructions carefully and complete the prescribed course to maximise effectiveness.

Who Should Avoid Aciclovir Tablets?

Aciclovir is generally safe for most individuals, but there are some exceptions. If you have a history of allergic reactions to aciclovir or any of its ingredients, you should avoid taking this medication. Always inform your doctor of any known allergies or pre-existing conditions, as this will help them tailor the treatment to your needs.

Potential Side Effects

Although aciclovir is typically well-tolerated, like any medication, it may cause side effects in some people. Common side effects can include mild symptoms such as nausea, headache, abdominal pain, dizziness, and fatigue. Some individuals may also experience skin-related issues like itching, a rash, or sensitivity to sunlight.

In rare cases, more serious side effects like kidney problems or neurological issues can occur, especially if the medication is not taken as prescribed or if you have underlying kidney issues. If you experience symptoms like confusion, tremors, or difficulty urinating, seek medical attention immediately.

Managing Your Cold Sore Outbreaks

If you frequently suffer from cold sores, managing the condition with aciclovir tablets can make a noticeable difference. Starting treatment at the first sign of an outbreak can shorten the duration and lessen discomfort. For people with a weakened immune system or those who experience multiple outbreaks each year, suppressive therapy with aciclovir tablets may be a more permanent solution to control the frequency and severity of cold sore episodes.

A virus causes cold sores, and while you can't completely eliminate the Herpes Simplex virus from your body, antiviral treatments like aciclovir can significantly improve your quality of life. By taking the prescribed dose on time and following the doctor’s recommendations, you can manage outbreaks effectively and prevent future flare-ups.

If you would like to book an appointment to discuss these antviral options, you can book an appointment here. Or you can always chat to the Healthwords chat.

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Dr Roger Henderson
Reviewed by Roger Henderson
Reviewed on 29.04.2024
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