Co-codamol

Co-codamol is suitable for adults and children aged 12 years and older, and dosing is age-dependent. It comes as tablets, capsules and effervescent tablets (dissolve them in water before swallowing), and you can take 1 to 2 doses every 6 hours, but no more than 4 times a day.

Acetaminophen and codeine can be dangerous if you take too much of them, so make sure you do not take any other acetaminophen or codeine-containing products at the same time as taking co-codamol.

Yes, it’s possible to become addicted to co-codamol if you take it for too long. Codeine belongs to a family of drugs called opioids. Opioids activate receptors in the brain and spinal cord to give us feelings of pain and pleasure. They block pain signals and release large amounts of dopamine, which can give us a good feeling, and we seek to repeat the experience. We also feel unwell without it. This is called dependency. It also carries the risk of tolerance with prolonged use, whereby you need to keep increasing the dose to have the same effect.

Do not take co-codamol if you have previously had an allergic reaction to acetaminophen, codeine, or another ingredient listed in the medication or an allergic reaction to any other opioid in the past. It is not suitable for children under 12 years. Speak with your doctor or pharmacist before taking co-codamol if you are pregnant or breastfeeding, or have any medical conditions, especially liver disease.

Co-codamol can interact with other medicines, such as warfarin, cholestyramine, sleeping tablets, and other medicines that can cause drowsiness. If you take any prescription, over-the-counter or herbal medicines, ask your doctor or pharmacist to check if they are safe to take alongside co-codamol.

Common side effects can include constipation, drowsiness, headache, feeling sick, vomiting, a dry mouth, and sweating. If you experience drowsiness, it is best to avoid driving and drinking alcohol.